Select Page

Viewing archives for Alumni

“The greatest benefit to humankind”: Old Elizabethan’s “stunning breakthrough” in protein research wins him a Nobel prize

Old Elizabethan Sir Demis Hassabis has been awarded the Nobel prize for chemistry, jointly with a colleague at the AI company he founded and with an American scientist.

Demis (OE 1988–1990), who is the co-founder and CEO of AI company Google DeepMind, receives half of the prize with his DeepMind colleague, Dr John Jumper, for their work on predicting complex protein structures. The other half of the prize awarded by the Royal Swedish Academy of Sciences goes to Professor David Baker, from the University of Washington, for his work on protein design.

In their statement, the prize committee wrote: “Demis Hassabis and John Jumper have developed an AI model to solve a 50-year-old problem: predicting proteins’ complex structures. These discoveries hold enormous potential.

“Since the 1970s, researchers had tried to predict protein structures from amino acid sequences, but this was notoriously difficult. However, four years ago, there was a stunning breakthrough.

“In 2020, Demis Hassabis and John Jumper presented an AI model called AlphaFold2. With its help, they have been able to predict the structure of virtually all the 200 million proteins that researchers have identified.”

The Nobel Committee emphasised the global impact of AlphaFold2. It has been accessed by more than two million researchers from 190 countries. Examples of its many applications include: helping scientists to understand better antibiotic resistance; and creating images of enzymes that can decompose plastic.

Reacting to the news, Demis, 48, said: “It’s totally surreal to be honest, quite overwhelming.”

He explained the “funny sequence” through which he actually heard the news that he was a Nobel laureate. Since the committee did not apparently have a telephone number for him, they had reached him through a Teams call to his wife, who was working on her laptop at the time. After at first ignoring it, she answered it at around the third or fourth call. The caller then requested to be put in touch with Demis, whom they asked for Dr Jumper’s number.

Demis thanked his colleagues, including Dr Jumper, adding: “David Baker we’ve got to know in the last few years, and he’s done some absolutely seminal work in protein design. So it’s really, really exciting to receive the prize with both of them.”

The Nobel prize committee praised the work of Professor Baker, which he began in 2003, saying that he had “succeeded with the almost impossible feat of building entirely new kinds of proteins.”

The committee’s statement concluded: “Life could not exist without proteins. That we can now predict protein structures and design our own proteins confers the greatest benefit to humankind.”

The illustration above shows a selection of protein structures determined using AlfaFold2 (©Terezia Kovalova/The Royal Swedish Academy of Sciences).

 

 

Supporting our Silicon Valley set!

Three Old Elizabethan entrepreneurs in San Francisco have linked up and are now connecting with other alumni working in the world’s leading centre for technology companies.

Pavir Patel sent Headmaster Neil Enright the above photo of himself, Akshat Sharma and Richard Ou together in San Francisco. The three only discovered that they had the same alma mater through chance conversations, but, since then, they have created a group chat and have been expanding it to include more OEs in and around the Bay Area.

Mr Enright said: “Our alumni network has been growing rapidly in recent years, with leavers supporting each other, sharing professional opportunities and socialising together. Especially for alumni far from home, like Richard, Akshat and Pavir, it can be good to spend time with others who share a similar background. As a School, we are doing all we can to support such connections through our QE Connect social and business network.”

Richard (OE 2010–2015) said: “All three of us are founders looking to build billion-dollar companies in Silicon Valley. Quite a few QE boys that I’ve met in the US have been entrepreneurs, too, all having raised not so insignificant amounts of capital. It feels like we’re following in the footsteps of Demis Hassabis and Mustafa Suleyman, maybe a few years or a decade behind.” (Demis [OE 1988–1990] and Mustafa [1995–2002] were among the three co-founders of leading AI company DeepMind, formed in 2010.)

“What I am really excited about is more people from QE coming to the US. I think this is the place to be,” Richard added.

Pavir (OE 2003–2010) and Akshat (2012–2019) are part of the long-established international Entrepreneur First accelerator, which runs one of its four programmes in San Francisco. “However, they’d not met until after Pavir’s encounter with me,” says Richard. “I met Pavir at a FinTech AI hackathon hosted at the Digital Garage office in San Francisco. The conversation went something like this:”

Richard: “Where in the UK are you from?”

Pavir: “London, what about you?”

Richard: “I’m from London as well. Whereabouts?”

Pavir: “Stratford, and you?”

Richard: “Highgate”

Pavir: “I used to go to school up north of Highgate!”

Richard: “Really, where?”

Pavir: “QE Boys”

Richard: “Holy sh*t, I went to QE as well!”

Richard later met Akshat at the Entrepreneur First office.

As for Pavir and Akshat, they knew each other through being in the same accelerator, but did not realise the full extent of their connection until a conversation in a Waymo (self-driving car) turned to their backgrounds. “It was surreal,” said Akshat. “We were mates already and were speaking about our homes in the UK and school experiences…and there was a moment of realisation of ‘Wait a second – that sounds very familiar’ when we realised we both went to QE!”

Richard said he realised even before going to university where he needed to be to pursue his goal of founding and growing a startup. “I knew that if I wanted to do it, the only place I could was the US. The problem was that education in the US was so expensive – four years of a degree course can easily be $250,000.”

The solution he arrived at was to go to King’s College London, majoring in Physics (“my passion”) for his first degree and then come to the US for a Master’s degree at the University of Pennsylvania – “only two years!” He worked out some further ways to reduce the financial burden, including becoming a Resident Advisor (RA) – a peer mentor for other students – which comes with the major plus that free housing and food are provided.

The idea for his business came about when he graduated from ‘Penn.’ last year and was looking for a graduation photographer. “I realised it was really hard – there is not really any infrastructure for freelancing.”

With time on his hands, he worked out a plan for a business to put that right, checking that he had a Minimum Viable Business (MVB). He shared the plan with the photographer he had eventually found, Jerry Cai. “As soon as I pitched it to him, he said: ‘I want in.’”

The two became co-founders of Agorum, described on its website as “a freelancer marketplace connecting clients with skilled creatives”. They have started initially by focusing on freelancers who require a physical presence for their work – photographers, DJs and private chefs.

The process has not always been easy. “Funding was difficult at first. We tried raising funds last year when the economy was not doing very well.”

Since then, however, they have been scaling rapidly, and Richard is focused on taking the business global. Agorum was recently valued at $10m.

“I think what changed things was moving to the Bay area: I don’t think there is an eco-system like the Bay’s that exists anywhere else in the world.”

He acknowledged the help provided by his accelerator – VIP-X (different from Pavir’s and Akshat’s). VIP-X is run by the University of Pennsylvania’s Wharton business school and caters primarily for people associated with Penn. and Wharton. It takes no equity and offers what are essentially grants, not loans.

“I think one of the hardest parts of doing a startup is the loneliness and distance that comes with it,” said Richard. “Few people can relate.” In particular, he has found the constant need for absolute discretion about his plans for the business hard.  “As the CEO, there is only so much you can ever say.”

“As my role has changed from managing a team of 1.5 people to now a team of ten, the problems are constantly evolving.”

“The thing is persistence,” Richard said, stressing the importance of listening to clients, who sometimes provide the only clue as to a way forward.  “There is something about this gut instinct – and it usually comes from your customer. It becomes your driving force.”

Richard has no doubt as to the source of his strength. “When I look back at my time at QE, it was hard. A lot of homework and pressure. Retrospectively, that is what helped, giving me the resilience I am drawing on now. A lot of people have shared that with me, too. Things were always hard, but that raised your tolerance for a lot of things.”

For his part, Akshat is currently building a company called Orbit. The sad truth about the current digital age is that “we have never been historically unhappier,” he said. “Orbit will empower people by making mental health as transparent and actionable as physical health through a non-invasive brain wearable. Orbit is unlocking cognition by building the first foundation model of the brain!”

In addition to his work with Entrepreneur First, Akshat is part of the first cohort of Founders – the University of Cambridge’s own accelerator programme. He graduated from Cambridge in Biomedical Engineering last year, launching Orbit at the start of 2024.

“At the Neuro Optics Lab [in Cambridge], I developed the first, and only, brain computer interface using HD DOT, a novel imaging approach to track human brain function at comparable resolutions to an fMRI. This modality, being cheap, portable and high resolution, is uniquely positioned to create the foundation model of our brains!”

Akshat has won multiple awards at international conferences and is writing a first-author paper on the subject.

By leveraging the novel wearable technology, Orbit is focussing on making brain-tracking as simple and accessible as Fitbit made fitness-tracking – “all in the comfort of your favourite baseball cap or beanie!” as he put it.

“With each version, Orbit builds the largest, real-world brain data-sets to unlock new secrets about the way we perceive the world around us – our cognition. It starts by understanding mental workload and aims to progress to complex mental states, including anxiety, stress and depression. Each version helps us regain control of a new emotion, at each step regaining happiness through giving us a deeper understanding and control of our brain.”

Finally, Pavir Patel’s business is Outerop. Like Akshat’s start-up, it launched at the beginning of this year. Outerop helps grow businesses online using AI, making it easier for them to build high-quality, reliable Large Language Model (LLM) products and to start creating self-optimising LLM pipelines (a series of steps where the output of one is the input of the other). Its slogan is: “Build GenAI products your customers love.”

Since reading Economics at Nottingham, Pavir has, he said, “done all sorts – from incubating J P Morgan’s first AI startup doing NLP; setting up their FinTech team in Asia (Hong Kong was awesome!) and scaling Europe’s leading broker/crypto exchange, Bitpanda Pro, to spinning off a company with a Series A raise [a company’s first significant round of venture-capital financing] to launching an e-commerce business with my wife”.

Setting the seal on a memorable year: top A-level grades follow golden array of university offers

The biggest-ever Year 13 at Queen Elizabeth’s School are today celebrating a strong set of A-level results, maintaining an unbroken record of top-level academic performance stretching back almost two decades.

The benchmark figure for the proportion of grades at A*–B remains above 95% for the 19th consecutive year. In addition, more than half the grades awarded to QE’s 173 final-year pupils were again at the highest-possible grade, A*, with almost a quarter of the year group achieving straight A*s.

The results cap a year that has seen QE pupils amass a formidable collection of university offers: 62 of them came from Oxford and Cambridge, a new School record; no fewer than 55% of boys secured offers to a university in the World Top 5 QS rankings; and 22 of the UK’s 24 Russell Group made offers to QE applicants.

The Year 13 students sat a grand total of 582 A-levels – an increase of 40 over last year. While Economics, Mathematics and the Sciences remained as popular as ever, there was a surge in take-up of other subjects offered under the School’s wide curriculum, ranging from English and Music to Philosophy, Government & Politics and Product Design.

Headmaster Neil Enright said: “There are many, many happy QE students today who now look forward to taking up places on the best courses at the best universities in the world. My congratulations go to them both on their results and on the hard work and determination that led to them.

“After emerging from the pandemic, this year group really threw themselves into the huge range of extra-curricular opportunities delivered through our QE Flourish programme, and that was no doubt a factor in their success in gaining such stellar university offers.

“Moreover, they have benefitted from the expert guidance provided through our new QE Futures programme, preparing them not only academically, but also helping them find their path in life as they identify and develop interests and broader skills. We’ve always said that outstanding results are an outcome of an education at QE, not the sole purpose of one!”

Notwithstanding QE’s position among the UK’s educational élite handful of leading schools across both the independent and state sectors, there is no question of it resting on its laurels, Mr Enright added. “We are continually looking forward with advances in our digital strategy and pastoral curriculum, while seeking to enhance our estate to deliver further opportunities for participation and excellence.

“This year sees the opening of a new studio for drama and oracy; there has been much focus on helping students communicate orally, alongside being able to communicate in writing in projects and exams. We also have ambitious plans for future investments into sports facilities, following on from new facilities for music and robotics in recent years.”

The year group have excelled in a wide range of extra-curricular activities throughout their time in the Sixth Form. For example:

  • Two robotics teams flying the flag for Britain at the Battle for Vegas – the only teams from outside North America to attend the VEX event in the desert resort;
  • Arjun Patel, Nathan Woodcock and Tharun Dhamodharan reaching the national final of the Pro Corda chamber music festival for schools as part of an U19 Saxophone Quintet; and
  • Shivam Singh, Yash Patel and Om Patel winning a design competition run by Homerton College, Cambridge, with their project which aimed to protect construction workers’ hearing.

“We hope that students and parents can be proud of their efforts and achievements,” Mr Enright said. “School staff are on hand to work with anyone who needs support on results day and beyond.”

“Wherever our leavers are heading next, they should be equipped with the confidence, ability and responsibility to thrive. They have formed close friendships, and we have enjoyed seeing them grow as young adults. We are delighted to be welcoming them into our fast-developing alumni community, QE Connect, which provides them with opportunities to support one another in their future endeavours and to continue to help those following in their footsteps. They are Elizabethans for life!”

Click on any of the images below to see a selection of photos from results day.

At the top of his game! Head of Rugby bows out with special leadership award, with nine QE boys also winners

Teacher and Old Elizabethan James Clarke won QE’s first-ever Leader Award from the Jack Petchey Achievement Award Scheme, having been nominated by his pupils.

Mr Clarke (OE 1999–2004), who leaves QE this summer after a dozen years in the PE department, was presented with his award alongside nine student winners drawn from Years 10–12.

QE’s ten recipients received their awards just a few weeks after the death of businessman and philanthropist Sir Jack Petchey at the age of 98. The award scheme that bears his name recognises outstanding young people aged 11-25 across London and Essex.

Headmaster Neil Enright said: “Many congratulations to James. His passion for rugby is well-known, but the award also rightly recognises his commitment to helping students reach their full potential, both academically and in their extra-curricular activities. He takes with him our best wishes as he moves to a new position with Bermudan rugby.

“I also congratulate the nine pupils who have won awards for their contributions to School life, which covered a wide range of endeavour, from music to mentoring.”

Mr Clarke is pictured, top, receiving his award from the Deputy Mayor of the Barnet, Councillor Danny Rich, and then at Sports Day, where he anchored the staff team to victory in the day’s traditional finale, a 16 x 100m relay known as the QE Mile. He received the Leader award for his dedication to coaching and mentoring, recognising that this has gone beyond the rugby field.

Pupils winning awards were:

  • Harrison Lee, Shrey Tater​, Chanul Athukoralage​ and Shreyas Mone​ in Year 12
  • Karan Somani​, Sejal Bobba​ and Muhammad Ammaar Hurzuk​ in Year 11
  • Noah Morley​ and Ahsan Rahman in Year 10.

Harrison Lee has led junior strings and various music ensembles, dedicating himself to enhancing their performances. He also consistently plays in School concerts, thus showcasing his passion for Music.

Shrey Tater is also involved with Music, with his contributions to the Senior Choir being recognised, along with his commitment to helping with extra-curricular activities, particularly with the younger years.

Shreyas Mone’s award reflected his role as an ambassador for the International Astronomy and Astrophysics Competition (IAAC). ​The citation added: “He is also known for his exceptional and captivating Physics blog, where he shares fascinating insights, making complex concepts easily understandable.”

Sejal Bobba is a candidate for the Barnet Youth Parliament, known for his role as a positive influence and role model for younger generations. He is actively involved in the School’s debating society and was also recognised for his friendly personality, always being willing to engage in conversations with anyone needing help.​

For the two youngest award-winners, Ahsan Rahman was reported to shine as a peer mentor, providing valuable support to new Year 7 boys dealing with examination stress and sharing strategies to avoid low grades. A committed sportsman and strong coach, he leads by example, on and off the field. ​

And Noah Morley is another exceptional musician, participating in six Music clubs per week and in numerous concerts. In addition to engaging in sports, he also contributes to the School community by assisting with House assemblies.​

Setting a positive example: high-flyers recognised at Junior Awards

Pupils from across the first three years of Queen Elizabeth’s School had their achievements recognised and lauded at the 2024 Junior Awards.

At an afternoon ceremony held in the Main School Hall, boys gathered with their families and with staff and dignitaries to celebrate.

There were prizes for all the classroom subjects, as well as House prizes, prizes for commitment, and prizes for extra-curricular activities, such as debating & public speaking, and chess. Music prizewinners from Years 7, 8 and 9 punctuated the programme with a series of musical interludes. A vote of thanks was given by the Year 7 debating & public speaking prizewinner, Aaron Singh.

Headmaster Neil Enright spoke about how the prizewinners are seen by others; guest of honour Asif Ahmed (OE 1997–2004) about how they see themselves; and the Mayor of Barnet, Councillor Tony Vourou, about how the whole School is seen in the borough: there is, he said, considerable pride in QE and the achievements of its students.

In his introduction to the ceremony, Mr Enright told the boys: “These awards are a signal that you are doing very well indeed and that we see in you qualities that set a positive example for others in the School – so many of whom are also very talented and hard working.”

He spoke about the butterfly effect, which argues that small things can end up having significant impacts, citing the famous story of a butterfly flapping its wings in one part of the world and a hurricane developing in another.

He urged the boys to small acts of kindness – “a quiet, unshowy altruism” – to benefit those around them, whether at School or elsewhere.

“With your abilities, many of you may go on to make the discoveries, find the cures, engineer the projects, secure the investments of the future. There should be no ceiling to your aspirations. But, with certainty, everyone here and in our Elizabethan community can do the little things in daily life so that things are better for others, or at least,” he added, quoting from George Eliot’s Middlemarch, “that things are ‘not so ill as they might have otherwise been’.”

Guest of honour Asif leads the accounting and advisory team at major accountancy firm Cooper Parry which focuses on venture capital-backed founders of companies. He is also the author of best-selling book The Finance Playbook for Entrepreneurs. An accomplished sportsman, he is now part of the Board at Middlesex County Cricket Club.

In his speech, he included many biographical elements from his Schooldays, mentioning being made form captain in Year 7, playing cricket for Middlesex and rugby for Hertfordshire, being appointed a Lieutenant, and achieving good grades.

“At all those milestones, including being appointed Lieutenant, I never shook the feeling of looking around me and thinking: ‘When will you get found out, you absolute fraud?’” he said.

After leaving School, while still training for his professional qualifications with large accountancy firm PwC, his father was diagnosed with a terminal illness. “I unexpectedly found myself in a position at 22 years old, looking after his very small accounting firm. There I was, no clue in the world, with nothing and really no-one to rely upon. The imposter syndrome kicked in again.”

Over time, however, Asif succeeded in building up the business, wrote his best-selling book, and was approached by a much larger firm with an offer to buy his company. “Today, I am a Partner of that firm and I lead the largest team and portfolio of high-growth technology businesses in the country, working with the best entrepreneurs in this land.”

He told the boys all this, because, he said: “I’ve come to realise that imposter syndrome is the world’s way of telling you that other people see something in you that you yourself can’t see…yet. When you are rewarded, you absolutely must savour it, hold it tightly and mark it out as one step closer to fulfilling your destiny.”

The afternoon’s music was a varied selection – including Stravinsky, Gershwin and Mozart alongside a piece by the rather less well-known Polish composer, Szymanowski.

Because of the inclement weather, the reception, normally held on Stapylton Field, took place this year in the Mayes Atrium.

  • Click on the thumbnails below to view the images at full size.
“You’ve had the golden ticket: now shine!” Final inspiration for leavers at Valediction

Lord Simon Woolley, Principal of Homerton College, Cambridge, challenged this year’s leavers to make the world a better place when he came to QE as guest speaker for Valediction.

All of Year 13 gathered in the Shearly Hall with their parents for the ceremony – a last chance to celebrate the contribution of the Class of 2024 to Queen Elizabeth’s School and to mark the start of their new status as Old Elizabethans.

As well as presentations to all leavers and music played by the School’s senior musicians, the afternoon included a prizegiving for those who had excelled in their studies and extra-curricular activities.

Headmaster Neil Enright said: “This was a super afternoon, with a great atmosphere. Lord Woolley was a brilliant and charismatic guest speaker. Amusing and inspiring in his address, he then happily spent time at the afternoon tea reception speaking to the students and their families.

“Everyone seemed to enjoy themselves, even if, after all the miserable weather we’ve had this year, it was possibly just a little too hot and sunny for some!”

In his address, the Headmaster told the leavers: “You sit here holding the most spectacular array of university offers of any Elizabethan cohort to date. Collectively, you’ve received offers from 46 UK institutions across 187 individual courses, including from 22 of the 24 Russell Group unis. We know that this year has seen a record 62 Oxbridge offers and, perhaps even more staggeringly, 55% of you hold offers from a World Top 5 university.”

Not only did many of them, now 18, have their first opportunity to vote in the forthcoming General Election, but many more opportunities were now available to them in life more generally.

“You are always welcome at Queen Elizabeth’s and can be part of our community for as long as you like. There is a growing network, online and in person, from which you can hopefully benefit. Do keep in touch,” the Headmaster concluded.

Year 13’s Darren Lee, who was School Captain in 2023, delivered an entertaining speech: “Though some of us may look different, with growth spurts and beards, we are the same 192 who sat the entrance test and joined in Year 7….. We did it and we did it together.”

He acknowledged the facilities and extra-curricular opportunities the School provides, as well as the care of the teachers, while noting that some of the best ‘lessons’ came from spending time with each other: the experience is as much about the moments around and between lessons, as what happens within them, he said. He implored his peers to keep in touch.

The guest speaker, who is Baron Woolley of Woodford, became Principal of Homerton in October 2021 ­– the third Black person to be elected head of a college at Cambridge or Oxford. He sits as a cross-bencher in the House of Lords. He has a focus on building consensus across political and community lines, and is passionate about educational access and supporting those with potential who are marginalised.

Lord Woolley began by celebrating the role of parents and families, asking them to stand up to be applauded by the boys. Having an 18-year-old son of his own, he identified with them, saying he knows it is not always easy, but is absolutely worth it. He celebrated the staff of the School, reminding the leavers that they turn up each day “to educate you, but also to make you shine”. They genuinely care and want you to succeed, he said.

He also called back up some individual students who had caught his attention: Darren Lee (“Our future Prime Minister!”) for his leadership and eloquent speech; Isher Jagdev (Latin prize winner) to help him with the Latin that he will need on Saturday when he conducts the graduation ceremony for Homerton undergraduates at the Senate House in Cambridge; and Nathan Woodcock (“Mr 100%”) whose perfect attendance had been noted. “To achieve change you have to be present; you have to turn up. He’s someone I’d want on my team.”

He spoke a little about his journey from a tough council estate in Leicester, where you had to learn to fight and where “the reason to go to school was to see your mates”. No one went to university from his school, but, he told the leavers: “You are going to the best universities on the planet.” Coming to Queen Elizabeth’s School was like being among the winning children in Roald Dahl’s Charlie and the Chocolate Factory: “You’ve had the golden ticket. Not everyone gets that chance, so the question is: what are you going to do with it?

“Be the people to stand up to inequality, to help people out of poverty, to find the cure, or build something better. The Headmaster and I are not asking you to be brilliant, to share your abilities, to make an impact on the world… we are demanding it. Not everyone can be the principal or the CEO, but every one of you can do something that makes a difference.”

The music during the afternoon included a remix composed by Indrajit Datta, as well as a medley of popular hits that had formed the soundtrack to their school years, played by Indrajit’s Year 13 peers.

Music during the afternoon tea outside following the ceremony was played by the Year 8 and 9 Music Colours winners.

  • Click on the thumbnails below to view the images.